http://www.redkawa.com/sofatube/
It's a big interface for YouTube that's designed for the PS3 and Wii, but it could also be used on HTPCs and media center PCs.
Here's a similar page for Flickr browsing:
http://www.airtightinteractive.com/proj ... owser/app/
Have fun with that.
EDIT: I changed the title so people might actually look at this thread.